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Sensitivity analyses using MR-Egger, weighted median, weighted mode, simple mode, maximum likelihood, and RAPS (Supplementary Table S4) showed consistent directionality of effects for schizophrenia, anxiety disorders, and autism

These data support the calculation of the Maximum Recommended Starting Dose (MRSD) the starting dose for the first administration in humans, derived from preclinical data and converted to a human equivalent dose using internationally agreed methods

This creates a proportional issue: If caloric intake falls by 3050%, micronutrient intake may also fall unless dietary density increases

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